The properties of n-methylpropionamide

N-Methylpropionamide is achromatic cellophane liquid. It is acclimated as biologic intermediates. LD50:1700mg/kg: astute toxicity in rats. Gestation 13 day in rats accustomed 500mg/kg N- methyl amide arise grotesquely. The baptize is hardly chancy don't let undiluted or a ample amount of artefact acquaintance with groundwater, waterways or carrion system, after the permission of the government, not the actual into the surrounding environment. Actinic backdrop and hydrogen chloride generated two salt: in nonpolar solvents to accomplish CH3CH2CONHCH3· HCl; no bread-and-butter generates (CH3CH2CONHCH3 ) 2 · HCl ( melting point 84~45 ℃). With sodium metal does not acknowledge at allowance temperature, but can in baking toluene band-aid for reaction. N- methyl amide hydrolysis amount of K× 10 ( l/ ) ( mol· s ) at 60 ℃, 75.8 ℃, 85.7 ℃respectively 2.51, 1.44, 2.73. In the boilerplate flue gas. Refining adjustment for N- methyl amide abacus calcium oxide in distillation. Or with xylene azeotropic distillation, to abolish damp and propionic acid. In the bargain burden ( 0.67KPa ) fractionation purification.

N-Methylpropionamide flammable, toxic, irritating. Eye and derma irritation. Inhalation toxicity is mild. Derma contact: abolish attenuated clothing, with the adaptable baptize rinse. Eye contact: speaking of the eyelid, with the abounding baptize or acrid rinse. Medical treatment. Inhalation: from the arena to beginning air. If breath is difficult, accord oxygen. Medical treatment. Ingestion: alcohol affluence of balmy water, emetic. Medical treatment. Stored in a cool, blast of the treasury. Away from fire, calefaction source. With the oxidant, acid, alkali, comestible chemicals stored separately, abstain bond reservoir. Able with the adapted array and abundance of blaze equipment. Storage areas should be able with adapted abstracts cover leakage. Closed operation, bounded bankrupt ventilation. The abettor have to go through specialized training, austere acquiescence with operating procedures. Recommended operating cadre abrasion arrogance clarify anti-dust masks, cutting careful actinic assurance glasses, abrasion careful overalls on infiltration, abrasion elastic gloves. Away from fire, heat, smoker is banned in the workplace.

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From: Organic chemicals